Reprogramming the Local Lymph Node Microenvironment Promotes Tolerance that Is Systemic and Antigen Specific
نویسندگان
چکیده
منابع مشابه
Stromal cells confer lymph node-specific properties by shaping a unique microenvironment influencing local immune responses.
Lymph nodes (LN) consist not only of highly motile immune cells coming from the draining area or from the systemic circulation, but also of resident stromal cells building the backbone of the LN. These two cell types form a unique microenvironment which is important for initiating an optimal immune response. The present study asked how the unique microenvironment of the mesenteric lymph node (m...
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2016
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2016.08.033